Fast bowler James Anderson will miss England's Test matches against Bangladesh to rest a knee injury, the England and Wales Cricket Board (ECB) said on Thursday.
However, the 21-year-old, who had been in doubt, will be available for the one-day series against Bangladesh and the Test and one-day series in Sri Lanka.
"Losing James for the Bangladesh tests is a blow but he is a young bowler who has borne a heavy workload this summer," chairman of selectors David Graveney said in a statement.
"Having consulted the medical team we feel that this decision is in his best long-term interests."
ECB chief medical officer Peter Gregory said Anderson had an "overuse injury" to one of the tendons in his left knee that would need rest.
Anderson is to also undergo a strengthening programme on the knee before flying to Dhaka on October 28 for the one-day matches.
The England selectors will announce a replacement for Anderson next week ahead of the Test squad's departure for Bangladesh on October 7.
Anderson has been an integral part of the England set-up since he made his international debut in a one-day series against Australia last December.
Despite his lack of experience, he was included in the team for this year's World Cup in Southern Africa where he took a career-best 4-25 against Namibia.
In June, he became the first Englishman to claim a one-day hat-trick during the series against Pakistan.
Anderson also impressed on his Test debut against Zimbabwe at Lord's where he collected five wickets.
England are playing two Tests and three one-dayers on the Bangladesh tour, which runs from October 12 to November 12.
They then play Sri Lanka in three one-day internationals before a three Test series from November 18 to December 22.
