Fast bowler Makhaya Ntini kept South Africa in the hunt on the first day of the second Test against Pakistan on Friday.
Pakistan were 135 for six in reply to South Africa's first innings of 124 at stumps.
A bristling bowling display by Ntini saw him take four for 18 from 10 overs.
South Africa's total was their lowest against Pakistan, breaking the record of 214 set in Faisalabad in the 1997-98 season.
Earlier, Pakistan's fast bowler Shoaib Akhtar, who last played a Test against India in Karachi in February, took four wickets for 36 to restrict the home side.
He was banned from cricket for two years in November after testing positive for banned substances but was later acquitted.
He first struck in the fifth over when AB de Villiers played a ragged shot to a wide delivery and was caught behind by wicketkeeper Kamran Akmal for two.
Four overs later Hashim Amla, who scored five, attempted to leave a legside delivery from Shoaib and gloved a catch to Akmal.
Graeme Smith stood firm for 44 balls for his innings of 28, which ended when he edged leg spinner Danish Kaneria onto Akmal's gloves only for Younis Khan to take the catch at slip.
Ashwell Prince then played a wild cut to a delivery from fast bowler Mohammad Sami and was dropped by Akmal.
But four balls later Prince, who scored two, repeated the stroke and this time Akmal took the catch.
Herschelle Gibbs, playing pending his appeal against a two-Test ban, was dropped by Younis and Akmal but with his next ball Kaneria trapped the South African in front for two.
Jacques Kallis and Mark Boucher took South Africa to lunch on 64 for five, but they were soon 83 for six when Kallis edged a ball from Shoaib to Akmal for 24. South Africa's tail fell away and they were all out in 40 overs.
Pakistan though lost their first wicket without a run on the board when Imran Farhat edged the eighth ball of the innings by fast bowler Makhaya Ntini to De Villiers at third slip.
Tea was taken immediately after Mohammad Hafeez, who had earlier been dropped, tried to pull another Ntini delivery and sent a gentle catch to Amla at short leg.
Scorecard
South Africa (1st innings):
A de Villiers c Kamran Akmal b Shoaib Akhtar 2
G Smith c Younis Khan b Danish Kaneria 28
H Amla c Kamran Akmal b Shoaib Akhtar 5
J Kallis c Kamran Akmal b Shoaib Akhtar 24
A Prince c Imran Farhat b Mohammad Sami 2
H Gibbs lbw b Danish Kaneria 2
M Boucher c Younis Khan b Danish Kaneria 35
S Pollock c Mohammad Sami b Shoaib Akhtar 4
A Nel c Danish Kaneria b Mohammad Asif 10
M Ntini not out 0
P Harris c Yasir Hameed b Mohammad Asif 4
Extras: (lb-3 nb-5) 8
Total: (all out, 40 overs) 124
Fall of wickets: 1-9, 2-27, 3-40, 4-49, 5-58, 6-83, 7-89, 8-120, 9-124.
Bowling: Shoaib Akhtar 11-2-36-4 (nb-2), Mohammad Asif 9-2-34-2, Danish Kaneria 14-3-36-3, Mohammad Sami 6-1-15-1 (nb-3).
Pakistan (1st innings):
Mohammad Hafeez c Amla b Ntini 13
Imran Farhat c De Villiers b Ntini 0
Younis Khan c Gibbs b Ntini 45
Yasir Hameed c De Villiers b Ntini 2
Mohammad Yousuf lbw b Pollock 32
Kamran Akmal c Prince b Nel 33
Mohammad Sami not out 0
Extras: (b-4 lb-5 w-1) 10
Total: (for six wickets, 40.2 overs) 135
Fall of wickets: 1-0, 2-17, 3-19, 4-79, 5-135, 6-135.
To bat: Inzamam-ul-Haq, Shoaib Akhtar, Danish Kaneria, Mohammad Asif.
Bowling: Nel 12.2-2-36-1 (w-1), Ntini 10-5-18-4, Kallis 8-0-39-0, Pollock 7-1-23-1, Harris 3-1-10-0.
