Out of form South African middle-order batsman J P Duminy has returned home owing to injuries, making him unavailable for the third and final One-dayer against India in Ahmedabad on Saturday.
Duminy, who sustained a left hand injury during the second ODI in Gwalior, also developed tooth pain and took the flight back home on Thursday.
"He had developed tooth pain and left last night," South Africa's media manager Micheal Owen-Smith said.
Duminy has had a horrendous run in the series and was dismissed for a duck in the Gwalior ODI which India won to take an unassailable 2-0 lead in the three-match series.
South Africa's coach Kepler Wessels said the injury lay off would help rejuvenate Duminy, an explosive batsman when in prime form.
"We mentioned a few technical and psychological aspects that we would like him to work on. It's a good thing that he will now go and play in the Indian Premier League where the pressure is not so intense and he will be able to regain his confidence," Wessels told Supersport.
In his last eight international innings, Duminy has managed 58 runs, including four first-ball ducks.
"It is not unusual for young players to start struggling after early success once opponents start making plans for them. In that case it's the young player's task to find a counter. JP has the world's talent and I believe he can fight back," Wessels said.